It was exciting to see today that Science Magazine called cancer immunotherapy the breakthrough of 2013. The author Jennifer Couzin-Frankel calls it a “breakthrough strategy” and though she admits the approach is not yet widespread, she highlights promising clinical trials that have stacked up this year. “Immunotherapy marks an entirely different way of treating cancer-by targeting the immune system, not the tumor itself,” she wrote. The article deals mainly with experiments focused on activating T cells by blocking surface proteins that shut T cells down. To learn more about other approaches, see my post about cancer vaccines.